Significats de glucocorticoid resistance en anglès

Cohen himself published some of the early work on glucocorticoid resistance.

Other research has shown that this acts as a surrogate measure of glucocorticoid resistance.

While animal work showing that chronic stress affects glucocorticoid resistance is persuasive, it is not definitive.

Cohen realised that data from two of his previous studies could be used to test this glucocorticoid resistance theory.

He knows, for example, of another group of researchers planning a study of the role of glucocorticoid resistance in asthma.

Familial glucocorticoid resistance is a hypertensive, hyperandrogenic disorder characterized by increased serum cortisol concentrations in the absence of stigmata of Cushing's syndrome.

These results suggest that glucocorticoid resistance in this family is due to a point mutation in the steroid-binding domain of the glucocorticoid receptor.

In a second study, Cohen had made direct measurements of glucocorticoid resistance in a group of 79 subjects before exposure to cold viruses.

The kinetic data obtained argue against the involvement of 11 beta-hydroxysteroid dehydrogenase as a modulating factor for the glucocorticoid resistance observed in guinea pigs.

The experiment revealed that prolonged stress is correlated not only with the likelihood of developing a cold, but also with higher levels of glucocorticoid resistance.